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The oral administration of Fusobacterium nucleatum significantly elevated the plasma triglyceride and cholesterol levels in ApoE / mice fed a high-cholesterol diet, promoting the onset and development of atherosclerosis 101

Across the 19 variants, only those in PNPLA3 - SAMM50 - PARVB gene complex showed statistically significant associations for higher fibrosis and MAS score with the highest risk for the PNPLA3 rs738409 SNP (Figure 1)

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Neurosci Lett 469(3):3337 Gano LB, Liang LP, Ryan K, Michel CR, Gomez J, Vassilopoulos A et al (2018) Altered mitochondrial acetylation profiles in a kainic acid model of temporal lobe epilepsy